Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Fgf10tm1.1Sms
Name:	fibroblast growth factor 10; targeted mutation 1.1, Suzanne L Mansour
MGI ID:	MGI:3526181
Gene:	Fgf10  Location: Chr13:118851199-118928651 bp, + strand  Genetic Position: Chr13, 67.14 cM, cytoband A3-A4
Alliance:	Fgf10tm1.1Sms page

Germline Transmission:	Earliest citation of germline transmission: J:150706
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Null/knockout) Mutation:    Insertion   Mutation details: A Neo+KanR cassette was placed in intron 1 and exon 2 was flanked by loxP sites. Exon 2 was subsequently removed by cre-mediated recombination. (J:150706)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	85 assay results 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	4 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Fgf10 Mutation:	33 strains or lines available

Original:	J:150706 Abler LL, et al., Conditional gene inactivation reveals roles for Fgf10 and Fgfr2 in establishing a normal pattern of epithelial branching in the mouse lung. Dev Dyn. 2009 Jul 17;238(8):1999-2013
All:	9 reference(s)