Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Rr320tm3.1Mkg
Name:	regulatory region 320; targeted mutation 3.1 Mark Groudine
MGI ID:	MGI:3525615
Synonyms:	delta5,6deltaH, Hbb-artm3.1Mkg
Gene:	Rr320  Location: Chr7:103501973-103526752 bp, + strand  Genetic Position: Chr7, Syntenic
Alliance:	Rr320tm3.1Mkg page

Germline Transmission:	Earliest citation of germline transmission: J:51229
Parent Cell Line:	AK7 (ES Cell)
Strain of Origin:	129S4/SvJaeSor

Allele Type:    Targeted (Modified regulatory region, Null/knockout) Mutation:    Intragenic deletion   Mutation details: The 5'DNAse I hypersensitive sites 5 and 6 were replaced with a loxP site flanked hygromycin resistance gene cassette. Upon crossing with CMV-cre deleter mice, the hygro cassette was excised, leaving a single loxP site in place of 5' HS5 and 6. (J:51229)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rr320 Mutation:	0 strains or lines available

Original:	J:51229 Bender MA, et al., Description and targeted deletion of 5' hypersensitive site 5 and 6 of the mouse beta-globin locus control region. Blood. 1998 Dec 1;92(11):4394-403
All:	2 reference(s)