Summary | Mutation origin | Mutation description | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol:	Abca1tm1Blt
Name:	ATP-binding cassette, sub-family A member 1; targeted mutation 1, Horst Bluethmann
MGI ID:	MGI:3525100
Gene:	Abca1  Location: Chr4:53030787-53159895 bp, - strand  Genetic Position: Chr4, 28.57 cM, cytoband A5-B3
Alliance:	Abca1tm1Blt page

Germline Transmission:	Earliest citation of germline transmission: J:95088
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	C57BL/6

Allele Type:    Targeted (Null/knockout) Mutation:    Insertion     Insertion of a neomycin resistance cassette into exon 2 disrupted the gene. (J:95088)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Abca1 Mutation:	88 strains or lines available

Original:	J:95088 Nofer JR, et al., Impaired platelet activation in familial high density lipoprotein deficiency (Tangier disease). J Biol Chem. 2004 Aug 6;279(32):34032-7
All:	1 reference(s)