Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Rapsntm1Jrs
Name:	receptor-associated protein of the synapse; targeted mutation 1, Joshua R Sanes
MGI ID:	MGI:2148091
Gene:	Rapsn  Location: Chr2:90865965-90876074 bp, + strand  Genetic Position: Chr2, 50.44 cM
Alliance:	Rapsntm1Jrs page

Germline Transmission:	Earliest citation of germline transmission: J:28777
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A neomycin resistance cassette replaced approximately 1kb of genomic sequence including part of exon 3 and intron 3. Western blot analysis did not detect the protein in muscle of homozygous mutant mice. (J:28777)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Rapsn Mutation:	31 strains or lines available

Original:	J:28777 Gautam M, et al., Failure of postsynaptic specialization to develop at neuromuscular junctions of rapsyn-deficient mice [see comments]. Nature. 1995 Sep 21;377(6546):232-6
All:	13 reference(s)