Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Prop1tm1Sac
Name:	paired like homeodomain factor 1; targeted mutation 1, Sally A Camper
MGI ID:	MGI:3521736
Synonyms:	Prop1-
Gene:	Prop1  Location: Chr11:50841633-50844584 bp, - strand  Genetic Position: Chr11, 30.95 cM
Alliance:	Prop1tm1Sac page

Germline Transmission:	Earliest citation of germline transmission: J:94409
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion     Sequence spanning from the ATG in exon 1 to part of exon 2 was replaced with a LacZ-neo cassette. (J:94409)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

10 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Prop1 Mutation:	15 strains or lines available

Original:	J:94409 Nasonkin IO, et al., Pituitary hypoplasia and respiratory distress syndrome in Prop1 knockout mice. Hum Mol Genet. 2004 Nov 15;13(22):2727-35
All:	7 reference(s)