Txnrd2tm2.1Marc
Targeted Allele Detail
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| Symbol: |
Txnrd2tm2.1Marc |
| Name: |
thioredoxin reductase 2; targeted mutation 2.1, Marcus Conrad |
| MGI ID: |
MGI:3512412 |
| Synonyms: |
TrxR2-[lacZ k.i.] |
| Gene: |
Txnrd2 Location: Chr16:18245167-18297823 bp, + strand Genetic Position: Chr16, 11.41 cM
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| Alliance: |
Txnrd2tm2.1Marc page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:94136
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| Parent Cell Line: |
E14 (ES Cell)
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| Strain of Origin: |
129P2/OlaHsd
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| Allele Type: |
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Targeted (Null/knockout, Reporter) |
| Mutations: |
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Insertion, Intragenic deletion
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Mutation details: Crossing to a cre-deleter strain resulted in excision the 4 floxed exons and expression of beta-galactosidase in the atrium and ventricle of the heart and to a lesser extent in the liver.
(J:94136)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Txnrd2 Mutation: |
18 strains or lines available
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| Original: |
J:94136 Conrad M, et al., Essential role for mitochondrial thioredoxin reductase in hematopoiesis, heart development, and heart function. Mol Cell Biol. 2004 Nov;24(21):9414-23 |
| All: |
1 reference(s) |
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Analysis Tools
