Ippk<Gt(XA232)Byg> Gene trapped Allele Detail MGI Mouse (MGI:3511861)

Ippk^Gt(XA232)Byg
Gene trapped Allele Detail

Summary

Symbol:	Ippk^Gt(XA232)Byg
Name:	inositol 1,3,4,5,6-pentakisphosphate 2-kinase; gene trap XA232, BayGenomics
MGI ID:	MGI:3511861
Synonyms:	Ippk^{Gt(pGT0pfs)1Ucd}
Gene:	Ippk Location: Chr13:49574725-49618049 bp, + strand Genetic Position: Chr13, 25.25 cM
Alliance:	Ippk^Gt(XA232)Byg page

Mutation
origin

Mutant Cell Line:	XA232
Germline Transmission:	Earliest citation of germline transmission: J:99722
Parent Cell Line:	Other (see notes) (ES Cell)
Strain of Origin:	129P2/OlaHsd

Mutation
description

Allele Type:

Gene trapped (Null/knockout, Reporter)

Mutation:

Insertion of gene trap vector Vector: pGT0pfs Vector Type: gene trap

Mutation details: The gene trap vector inserted into the first intron of the gene. RT-PCR analysis on brain mRNA indicated that a transcript containing a fusion between the endogenous gene and the lacZ gene of the gene trap vector is expressed. (J:99722)

Sequence Tags:

Sequence tag details (1 tag)

Genome Context:

Genome Browser view of this mutation

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Expression

In Mice Carrying this Mutation:

29 assay results

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 2 strains available Cell Lines: 0 lines available
Carrying any Ippk Mutation:	41 strains or lines available

Notes

All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.

References

Original:	J:99722 Verbsky J, et al., Disruption of the mouse inositol 1,3,4,5,6-pentakisphosphate 2-kinase gene, associated lethality, and tissue distribution of 2-kinase expression. Proc Natl Acad Sci U S A. 2005 Jun 14;102(24):8448-53
All:	2 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/09/2024 MGI 6.23