Summary | Mutation origin | Mutation description | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol: Myo7aHdb Name: myosin VIIA; headbanger MGI ID: MGI:3511858 Synonyms: ABE6 Gene: Myo7a  Location: Chr7:97700267-97768731 bp, - strand  Genetic Position: Chr7, 53.57 cM Alliance: Myo7aHdb page

Stereocilia defects in Myo7aHdb/Myo7a+ mice Show the 4 phenotype image(s) involving this allele.

Strain of Origin:

C3HeB/FeJ

Allele Type:    Chemically induced (ENU) Mutation:    Single point mutation   Mutation details: An A to T transversion at position 531 in exon 6 of Myo7a was identified and is predicted to cause an isoleucine-to-phenylalanine amino acid substitution at position 178, however no evidence of complementation was found when homozygotes were mated with heterozygous Myo7a4626SB. (J:93998)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Myo7a Mutation:	118 strains or lines available

Original:	J:93998 Rhodes CR, et al., A Myo7a mutation cosegregates with stereocilia defects and low-frequency hearing impairment. Mamm Genome. 2004 Sep;15(9):686-97
All:	6 reference(s)