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Tg(CAG-Bgeo/ALPP)1Lbe
Transgene Detail
Nomenclature
Symbol: Tg(CAG-Bgeo/ALPP)1Lbe
Name: transgene insertion 1, Corrinne Lobe
MGI ID: MGI:3505556
Synonyms: Tg(ACTB-Bgeo/ALPP)1Lbe, Tg(CAG-Bgeo/ALPP)1Lbe, ZAP, Z/AP
Transgene: Tg(CAG-Bgeo/ALPP)1Lbe  Location: unknown  
Transgene
origin
Germline Transmission:  Earliest citation of germline transmission: J:93700
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Transgene
description
Transgene Type:    Transgenic (Reporter)
Mutation:    Insertion
 
Mutation detailsThe transgene contains the CMV enhancer/chicken beta-actin promoter, a floxed Beta-geo reporter/SV40 polyadenylation signal segment, and the human placental alkaline phosphatase gene followed by a rabbit Hbb polyadenylation sequence. In transgenic mice expression of lacZ is widespread, with notable exceptions being erythrocytes, chondrocytes and adipocytes. This expression is observed throughout all embryonic and adult stages. (J:93700)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Notes
Cre excision of lacZ and the neomycin resistance gene results in expression of the ALPP reporter.
References
Original:  J:93700 Lobe CG, et al., Z/AP, a double reporter for cre-mediated recombination. Dev Biol. 1999 Apr 15;208(2):281-92
All:  139 reference(s)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/04/2018
MGI 6.13
The Jackson Laboratory