Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Dmbt1tm1Qaa
Name:	deleted in malignant brain tumors 1; targeted mutation 1, Qais Al-Awqati
MGI ID:	MGI:3497714
Gene:	Dmbt1  Location: Chr7:130633787-130723357 bp, + strand  Genetic Position: Chr7, 73.2 cM, cytoband F4
Alliance:	Dmbt1tm1Qaa page

Germline Transmission:	Earliest citation of germline transmission: J:93477
Parent Cell Line:	MM13 (ES Cell)
Strain of Origin:	129S/SvEv

Allele Type:    Targeted (Null/knockout, Reporter) Mutations:    Insertion, Intragenic deletion   Mutation details: LacZ and a PGK-neo cassette replaced the first exon encoding the signal peptide via homologous recombination. Beta-galactosidase expression was first detected in the E3.5 inner cell mass. (J:93477)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Dmbt1 Mutation:	110 strains or lines available

Original:	J:93477 Takito J, et al., Conversion of ES cells to columnar epithelia by hensin and to squamous epithelia by laminin. J Cell Biol. 2004 Oct 27;166(7):1093-102
All:	1 reference(s)