Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Myf5tm1(Pdgfa)Sor
Name:	myogenic factor 5; targeted mutation 1, Philippe Soriano
MGI ID:	MGI:2135563
Synonyms:	Myf5PGDFA-N
Gene:	Myf5  Location: Chr10:107318769-107321995 bp, - strand  Genetic Position: Chr10, 55.95 cM
Alliance:	Myf5tm1(Pdgfa)Sor page

Germline Transmission:	Earliest citation of germline transmission: J:65301
Parent Cell Line:	AK7 (ES Cell)
Strain of Origin:	129S4/SvJaeSor

Allele Type:    Targeted (Inserted expressed sequence) Mutation:    Insertion   Mutation details: A Pdgfa cDNA was inserted between a SacI site and a KpnI site in the 5'UTR of the Myf5 gene. An adjacent loxP-flanked neomycin cassette was retained in this allele. Alteration in the expression pattern of Pdgfa was noted in homozygous mutant embryos as assayed by in situ hybridization. (J:65301)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Myf5 Mutation:	17 strains or lines available

Original:	J:65301 Tallquist MD, et al., Early myotome specification regulates PDGFA expression and axial skeleton development. Development. 2000 Dec;127(23):5059-70
All:	1 reference(s)