Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | Notes | References

Symbol:	Pax6Leca4
Name:	paired box 6; lens corneal adhesion 4
MGI ID:	MGI:1934618
Synonyms:	Gena368, GENA 368
Gene:	Pax6  Location: Chr2:105499245-105527709 bp, + strand  Genetic Position: Chr2, 55.31 cM
Alliance:	Pax6Leca4 page

Strain of Origin:

BALB/cAnN

Allele Type:    Chemically induced (ENU) Mutation:    Single point mutation   Mutation details: The mutation underlying the phenotype in Leca4 mice was identified as a C to A substitution at nucleotide position 354 of the Pax6 gene. The mutation occurs in exon 6 and introduces the Asn64Lys change in the Paired box domain of the protein. (J:75964) Inheritance:    Not Specified

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	3 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Pax6 Mutation:	90 strains or lines available

Original:	J:75964 Thaung C, et al., Novel ENU-induced eye mutations in the mouse: models for human eye disease. Hum Mol Genet. 2002 Apr 1;11(7):755-67
All:	5 reference(s)