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Cxcr4tm1Yzo
Targeted Allele Detail
Summary
Symbol: Cxcr4tm1Yzo
Name: C-X-C motif chemokine receptor 4; targeted mutation 1, Yong-Rui Zou
MGI ID: MGI:1934407
Synonyms: CXCR4-
Gene: Cxcr4  Location: Chr1:128515936-128520030 bp, - strand  Genetic Position: Chr1, 56.43 cM
Alliance: Cxcr4tm1Yzo page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:69255
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
    A loxP-flanked neomycin resistance cassette was inserted into the second exon. (J:69255)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 34 assay results
In Structures Affected by this Mutation: 6 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cxcr4 Mutation:  40 strains or lines available
References
Original:  J:69255 Zou YR, et al., Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development. Nature. 1998 Jun 11;393(6685):595-9
All:  32 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory