Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Tinf2tm1Yjc
Name:	Terf1 (TRF1)-interacting nuclear factor 2; targeted mutation 1, Y Jeffrey Chiang
MGI ID:	MGI:3052712
Synonyms:	Tin2-
Gene:	Tinf2  Location: Chr14:55912146-55919277 bp, - strand  Genetic Position: Chr14, 28.19 cM
Alliance:	Tinf2tm1Yjc page

Germline Transmission:	Earliest citation of germline transmission: J:92239
Parent Cell Line:	CJ7 (ES Cell)
Strain of Origin:	129S1/Sv-Oca2+ Tyr+ Kitl+

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A neomycin resistance gene was inserted into exon 1 upstream of the ATG. Southern blot and PCR confirmed recombination in mice. (J:92239)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tinf2 Mutation:	14 strains or lines available

Original:	J:92239 Chiang YJ, et al., Telomere-associated protein TIN2 is essential for early embryonic development through a telomerase-independent pathway. Mol Cell Biol. 2004 Aug;24(15):6631-4
All:	2 reference(s)