Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol: Rr29Hxl3 Name: regulatory region 29; hemimelic extra toes-like 3 MGI ID: MGI:3051414 Synonyms: M100081, ShhHxl3 Gene: Rr29  Location: unknown  Genetic Position: Chr5, Syntenic Alliance: Rr29Hxl3 page

Skeletal phenotypes of Rr29Hx/Rr29Hx and Rr29Hxl3/Shh+ mice Show the 1 phenotype image(s) involving this allele.

Strain of Origin:

C57BL/6J

Allele Type:    Chemically induced (ENU) (Modified regulatory region) Mutation:    Single point mutation   Rr29Hxl3 involves 1 genes/genome features (Lmbr1) View all   Mutation details: Generated by a large-scale ENU mutagenesis screen in RIKEN GSC. This mutation is the result of an A-to-G transition in a conserved Shh enhancer element located in intron 5 of the Lmbr1 gene. The mutation is located 145 bp 5' of the Hx mutation. Inheritance:    Dominant

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Rr29 Mutation:	2 strains or lines available

Original:	J:87798 Sagai T, et al., Phylogenetic conservation of a limb-specific, cis-acting regulator of Sonic hedgehog ( Shh). Mamm Genome. 2004 Jan;15(1):23-34
All:	3 reference(s)