Summary | Transgene origin | Transgene description | Phenotypes | Tumor data | Find Mice (IMSR) | Notes | References

Symbol:	Tg(MMTV-Erbb2)NB1Mul
Name:	transgene insertion NB1, William Muller
MGI ID:	MGI:3050875
Synonyms:	TG.NB
Transgene:	Tg(MMTV-Erbb2)NB1Mul  Location: unknown
Alliance:	Tg(MMTV-Erbb2)NB1Mul page

Strain of Origin:

FVB/N

Transgene Type:    Transgenic (Inserted expressed sequence) Mutation:    Insertion   Tg(MMTV-Erbb2)NB1Mul expresses 1 gene Transgene expresses: Organism Expressed Gene Homolog in Mouse Note rat Erbb2 (24337) Erbb2  (MGI:95410)   Mutation details: This transgene contains the MMTV (mouse mammary tumor virus) promoter and a 4.6 kb cDNA from the rat Erbb2 (avian erythroblastosis B2) oncogene. The activated form of the gene is used in this construct, which differs from the wild-type allele by a point mutation, Val664Glu. Six transgenic lines were produced (NA, NB, NF, NK, NL and NM). (J:48632)

View phenotypes and curated references for all genotypes (concatenated display).

List all tumor models in MMHCdb carrying Tg(MMTV-Erbb2)NB1Mul

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:48632 Muller WJ, et al., Single-step induction of mammary adenocarcinoma in transgenic mice bearing the activated c-neu oncogene. Cell. 1988 Jul 1;54(1):105-15
All:	1 reference(s)