Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Nrg1tm1Cbm
Name:	neuregulin 1; targeted mutation 1, Carmen Birchmeier
MGI ID:	MGI:1928489
Synonyms:	neuregulindelta7-9, Nrg-
Gene:	Nrg1  Location: Chr8:32299493-33381858 bp, - strand  Genetic Position: Chr8, 18.75 cM
Alliance:	Nrg1tm1Cbm page

Germline Transmission:	Earliest citation of germline transmission: J:29971
Parent Cell Line:	E14.1 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A neomycin resistance gene replaces exons 7, 8 and 9, which encode the carboxy-terminus of the EGF domain of all known Ngf1 variants. (J:29971)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	47 assay results
In Structures Affected by this Mutation:	15 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nrg1 Mutation:	53 strains or lines available

Original:	J:29971 Meyer D, et al., Multiple essential functions of neuregulin in development [see comments] [published erratum appears in Nature 1995 Dec 14;378(6558):753]. Nature. 1995 Nov 23;378(6555):386-90
All:	22 reference(s)