Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Hoxb1tm5Mrc
Name:	homeobox B1; targeted mutation 5, Mario R Capecchi
MGI ID:	MGI:1928090
Synonyms:	Hoxb1GFP
Gene:	Hoxb1  Location: Chr11:96256578-96259082 bp, + strand  Genetic Position: Chr11, 59.86 cM
Alliance:	Hoxb1tm5Mrc page

Germline Transmission:	Earliest citation of germline transmission: J:65599
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Null/knockout, Reporter) Mutation:    Insertion   Mutation details: GFP was inserted in-frame into the first coding exon of the Hoxb1 gene. An adjacent loxP flanked neomycin cassette was removed via a cre-mediated recombination event. (J:65599)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	161 assay results 3 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	3 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hoxb1 Mutation:	24 strains or lines available

Original:	J:65599 Gaufo GO, et al., Hoxb1 controls effectors of sonic hedgehog and mash1 signaling pathways. Development. 2000 Dec;127(24):5343-54
All:	9 reference(s)