Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Bub1btm1.1Jvd
Name:	BUB1B, mitotic checkpoint serine/threonine kinase; targeted mutation 1.1, Jan M A van Deursen
MGI ID:	MGI:3046581
Synonyms:	Bub1b-
Gene:	Bub1b  Location: Chr2:118428692-118472072 bp, + strand  Genetic Position: Chr2, 59.4 cM
Alliance:	Bub1btm1.1Jvd page

Germline Transmission:	Earliest citation of germline transmission: J:91128
Parent Cell Line:	TL1/TL-1 (ES Cell)
Strain of Origin:	129S6/SvEvTac

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: This allele is derived from Bub1btm1Jvd via cre mediated recombination, which excises exon 5 and results in out-frame fusion of exons 4 and 6. (J:91128)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Bub1b Mutation:	58 strains or lines available

Original:	J:91128 Baker DJ, et al., BubR1 insufficiency causes early onset of aging-associated phenotypes and infertility in mice. Nat Genet. 2004 Jul;36(7):744-9
All:	6 reference(s)