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Transgene Detail
Symbol: Tg(CAG-cat-lacZ)1Brn
Name: transgene insertion 1, Anton Berns
MGI ID: MGI:3044043
Synonyms: ACZL, floxLacZ, FLZI, loxP-CAT/loxP-LacZ, Tg(ACTB-cat-lacZ)1Brn, Tg(CAG-cat-lacZ)1Brn
Transgene: Tg(CAG-cat-lacZ)1Brn  Location: unknown  
Strain of Origin:  FVB/N
Transgene Type:    Transgenic (Reporter)
Mutation:    Insertion
Mutation detailsThe transgene comprises the CMV enhancer and chicken beta-actin promoter and the beta-galactosidase coding sequence separated by the chloramphenicol acetyltransferase (cat) gene flanked by loxP sites. Beta-galactosidase expression is blocked by presence of the cat gene; when the CAT sequence is excised by Cre recombinase, beta-galactosidase is expressed. (J:66884, J:80158)
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Original:  J:80158 Akagi K, et al., Cre-mediated somatic site-specific recombination in mice. Nucleic Acids Res. 1997 May 1;25(9):1766-73
All:  31 reference(s)

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MGI 6.12
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