Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Runx1tm3Spe
Name:	runt related transcription factor 1; targeted mutation 3, Nancy A Speck
MGI ID:	MGI:3043614
Synonyms:	floxed Runx1 allele, Runx1F, Runx1F
Gene:	Runx1  Location: Chr16:92398354-92622962 bp, - strand  Genetic Position: Chr16, 53.7 cM
Alliance:	Runx1tm3Spe page

Germline Transmission:	Earliest citation of germline transmission: J:90431
Parent Cell Line:	J1 (ES Cell)
Strain of Origin:	129S4/SvJae

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: LoxP sites were inserted to flank exon 4 of the locus. A neo and a third loxP site was downstream of the second loxP site in intron 4. Gene expression was not affected by the presence of the loxP sites. (J:107469)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	2 assay results 2 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	6 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Runx1 Mutation:	35 strains or lines available

Original:	J:90431 Li Z, et al., A new floxed allele of Runx1. MGI Direct Data Submission. 2004;
All:	51 reference(s)