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Symbol: |
Neu1c |
Name: |
neuraminidase 1; c variant |
MGI ID: |
MGI:3042797 |
Gene: |
Neu1 Location: Chr17:35150229-35154929 bp, + strand Genetic Position: Chr17, 18.48 cM
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Alliance: |
Neu1c page
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Strain of Origin: |
Not Applicable
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Allele Type: |
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Not Applicable |
Mutation: |
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Nucleotide substitutions
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Mutation details: Sequencing of the a allele revealed 4 nucleotide differences compared to the b allele. These changes alter the amino acid residues 11, 15, 17 and 19 of the encoded protein from Gly, Tyr, Ala and Arg to Arg, Cys, Val and Cys, respectively. This encoded protein has 2 fold greater activity than the protein encoded by the b allele as demonstrated in an in vitro assay.
(J:49430)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Neu1 Mutation: |
26 strains or lines available
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Original: |
J:6860 Chorney M, et al., Monoclonal antibody to an alloantigenic determinant on beta2-microglobulin (beta 2M) of the mouse. Immunogenetics. 1982;16(1):91-3 |
All: |
4 reference(s) |
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