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Tc-3H
Chemically induced Allele Detail
Summary
Symbol: Tc-3H
Name: brachyury, T-box transcription factor T; curtailed 3 Harwell
MGI ID: MGI:3042264
Gene: T  Location: Chr17:8653255-8661328 bp, + strand  Genetic Position: Chr17, 4.92 cM
Alliance: Tc-3H page
Mutation
origin
Strain of Origin:  BALB/cOlaHsd
Mutation
description
Allele Type:    Chemically induced (ENU)
Mutation:    Nucleotide substitutions
 
Mutation detailsThe Tc-3H allele is caused by a splice donor mutation at the end of exon 7. A protein truncation, either due to exon skipping or to read-through of the donor site causing an altered open reading frame beyond amino acid 344, is predicted. (J:93195)
Inheritance:    Semidominant
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any T Mutation:  60 strains or lines available
References
Original:  J:93195 Bogani D, et al., New semidominant mutations that affect mouse development. Genesis. 2004 Oct;40(2):109
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory