Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Hrrh-bmh
Name:	lysine demethylase and nuclear receptor corepressor; rhino-bald Mill Hill
MGI ID:	MGI:3039558
Synonyms:	hrrhbmh
Gene:	Hr  Location: Chr14:70789652-70810988 bp, + strand  Genetic Position: Chr14, 36.32 cM
Alliance:	Hrrh-bmh page

Strain of Origin:

C57BL/6JRj x CBA/JRj

Allele Type:    Spontaneous Mutation:    Intragenic deletion   Mutation details: The mutation in the bald Mill Hill mouse was determined to be a small 296 bp deletion of genomic DNA that includes part of exon 19 and the 3' UTR of the gene. The mutant allele is expressed in a similar pattern to the wild-type message. However the resulting protein is 150 rather than 130 kDa in size. (J:89321) Inheritance:    Recessive

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

6 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hr Mutation:	84 strains or lines available

Original:	J:89321 Brancaz MV, et al., A new allele of the mouse hairless gene interferes with Hox/LacZ transgene regulation in hair follicle primordia. Exp Mol Pathol. 2004 Apr;76(2):173-81
All:	3 reference(s)