Summary | Transgene origin | Transgene description | Phenotypes | Disease models | Find Mice (IMSR) | Notes | References

Symbol:	LeprTg(Mth11)1Aig
Name:	leptin receptor; transgene insertion 1, Bernhard Aigner
MGI ID:	MGI:1888983
Gene:	Lepr  Location: Chr4:101574601-101672549 bp, + strand  Genetic Position: Chr4, 46.96 cM
Alliance:	LeprTg(Mth11)1Aig page

Strain of Origin:

Him:OF1

Transgene Type:    Transgenic (Inserted expressed sequence) Mutation:    Intragenic deletion   Mutation details: The mutation was caused by insertion of a transgene. The construct contained 2.3 kb of the rabbit smooth muscle myosin heavy chain promoter region. The deletion extends from intron 17 into the 3' region of the gene. (J:61119) Inheritance:    Not Specified

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Lepr Mutation:	121 strains or lines available

Original:	J:61119 Reichart U, et al., Contrasting obesity phenotypes uncovered by partial leptin receptor gene deletion in transgenic mice. Biochem Biophys Res Commun. 2000 Mar 16;269(2):502-7
All:	1 reference(s)