Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Ext1tm1Dews
Name:	exostosin glycosyltransferase 1; targeted mutation 1, Dan E Wells
MGI ID:	MGI:1888710
Synonyms:	EXT1-
Gene:	Ext1  Location: Chr15:52931657-53209579 bp, - strand  Genetic Position: Chr15, 20.0 cM
Alliance:	Ext1tm1Dews page

Germline Transmission:	Earliest citation of germline transmission: J:64021
Parent Cell Line:	AB2.1 (ES Cell)
Strain of Origin:	129S7/SvEvBrd-Hprt1b-m2

Allele Type:    Targeted (Null/knockout, Reporter) Mutations:    Insertion, Intragenic deletion   Mutation details: A 0.3 kb genomic fragment containing part of exon 1 and intron 1 was replaced by a promoterless lacZ gene that was fused in frame with the exon 1 sequences. (J:64021)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	5 assay results
In Structures Affected by this Mutation:	3 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ext1 Mutation:	63 strains or lines available

Original:	J:64021 Lin X, et al., Disruption of gastrulation and heparan sulfate biosynthesis in EXT1-deficient mice. Dev Biol. 2000 Aug 15;224(2):299-311
All:	7 reference(s)