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Gpr37tm2Gtva
Targeted Allele Detail
Summary
Symbol: Gpr37tm2Gtva
Name: G protein-coupled receptor 37; targeted mutation 2, Glauco Tocchini-Valentini
MGI ID: MGI:3027995
Synonyms: Gpr-
Gene: Gpr37  Location: Chr6:25668522-25689979 bp, - strand  Genetic Position: Chr6, 11.65 cM
Alliance: Gpr37tm2Gtva page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:91390
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsMale Gpr37flox/+ mice were crossed to female mice carrying the Tg(CMV-cre)1Cgn transgene. Cre expression resulted in excision of exon 1. Absence of transcript in the resulting mice was verified by Northern blot analysis. (J:91390)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gpr37 Mutation:  34 strains or lines available
References
Original:  J:91390 Marazziti D, et al., Altered dopamine signaling and MPTP resistance in mice lacking the Parkinson's disease-associated GPR37/parkin-associated endothelin-like receptor. Proc Natl Acad Sci U S A. 2004 Jul 6;101(27):10189-94
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory