Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Gpr37tm1Gtva
Name:	G protein-coupled receptor 37; targeted mutation 1, Glauco Tocchini-Valentini
MGI ID:	MGI:3027992
Synonyms:	Gpr37flox
Gene:	Gpr37  Location: Chr6:25668522-25689979 bp, - strand  Genetic Position: Chr6, 11.65 cM
Alliance:	Gpr37tm1Gtva page

Germline Transmission:	Earliest citation of germline transmission: J:91390
Parent Cell Line:	E14.1 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: A single loxP site was inserted upstream of exon 1 and a floxed neomycin resistance cassette was inserted in intron 1. A properly targeted ES cell clone was transfected with pCre-Pac in vitro expression vector which eliminated the floxed neomycin gene and left exon 1 flanked by loxP sites. (J:91390)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gpr37 Mutation:	34 strains or lines available

Original:	J:91390 Marazziti D, et al., Altered dopamine signaling and MPTP resistance in mice lacking the Parkinson's disease-associated GPR37/parkin-associated endothelin-like receptor. Proc Natl Acad Sci U S A. 2004 Jul 6;101(27):10189-94
All:	1 reference(s)