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Ifi47tm1Gat
Targeted Allele Detail
Summary
Symbol: Ifi47tm1Gat
Name: interferon gamma inducible protein 47; targeted mutation 1, Gregory A Taylor
MGI ID: MGI:3027113
Gene: Ifi47  Location: Chr11:48967414-48987801 bp, + strand  Genetic Position: Chr11, 29.08 cM, cytoband B1.2
Alliance: Ifi47tm1Gat page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:87535
Parent Cell Line:  CJ7 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe entire coding region was replaced with a neomycin selection cassette inserted by homologous recombination. Western blot analysis of splenic and thymic lysates indicated an absence of protein in homozygous mutant mice. (J:87535)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ifi47 Mutation:  25 strains or lines available
References
Original:  J:87535 Collazo CM, et al., Inactivation of LRG-47 and IRG-47 reveals a family of interferon gamma-inducible genes with essential, pathogen-specific roles in resistance to infection. J Exp Med. 2001 Jul 16;194(2):181-8
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory