Tria1<STS/A> QTL Variant Detail MGI Mouse (MGI:2687415)

Tria1^STS/A
QTL Variant Detail

Summary | Variant origin | Variant description | Notes | References

Summary

QTL variant:	Tria1^STS/A
Name:	T cell receptor induced activation 1; STS/A
MGI ID:	MGI:2687415
QTL:	Tria1 Location: Chr11:53613565-53613855 bp Genetic Position: Chr11, cM position of peak correlated region/allele: 31.99 cM
QTL Note:	genome coordinates based on the marker associated with the peak LOD score

Variant
origin

Strain of Specimen:

STS/A

Variant
description

Allele Type:		QTL
Inheritance:		Not Specified

Notes

Mapping and Phenotype information for this QTL, its variants and associated markers

J:36501

The CcS-4 strain was found to exhibit a proliferation of T cells in response to Cd3 mAb. F2 hybrids between responder CcS-4 and parental BALB/c mice were examined to localize quantitative trait loci involved with control of this response. Tria1 was localized on mouse Chromosome 11 associated with marker D11Nds9 (P = 0.000023).

References

Original:	J:36501 Havelkova H, et al., Genetic control of T-cell proliferative response in mice linked to chromosomes 11 and 15. Immunogenetics. 1996;44(6):475-7
All:	1 reference(s)

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