Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Sox18Mhdadcc1
Name:	SRY (sex determining region Y)-box 18; Martin Hrabe de Angelis dark coat color 1
MGI ID:	MGI:2682755
Synonyms:	Dcc1, Sox18Gsfdcc1
Gene:	Sox18  Location: Chr2:181311630-181313433 bp, - strand  Genetic Position: Chr2, 103.71 cM
Alliance:	Sox18Mhdadcc1 page

Strain of Origin:

C3HeB/FeJ

Allele Type:    Chemically induced (ENU) Mutation:    Single point mutation   Mutation details: The mutation was identified as a T to A transversion that results in a nonsense mutation, Leu220ter, in the transactivation domain of the protein. (J:81301) Inheritance:    Semidominant

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Sox18 Mutation:	25 strains or lines available

Original:	J:81301 Fitch KR, et al., Genetics of dark skin in mice. Genes Dev. 2003 Jan 15;17(2):214-28
All:	1 reference(s)