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Targeted Allele Detail
Symbol: Slc45a2tm1(K14-A)R
Name: solute carrier family 45, member 2; targeted mutation 1, Oak Ridge National Laboratory
MGI ID: MGI:2681497
Synonyms: In(15)21Rk Matptm1(K14-A)R, In(15)21Rk-Matp+tm(k14-Agouti)1R, LE21Rk
Gene: Slc45a2  Location: Chr15:11000721-11029233 bp, + strand  Genetic Position: Chr15, 5.4 cM
Germline Transmission:  Earliest citation of germline transmission: J:91142
Parent Cell Line:  Other (see notes) (ES Cell)
Strain of Origin:  mixed
Allele Type:    Targeted (Not Applicable)
Mutation:    Insertion
Mutation detailsA PGK-neomycin-K14-Agouti minigene cassette was inserted in intron 2 of the Matp gene within the inverted region of In(15)21Rk. (J:91142)
View phenotypes and curated references for all genotypes (concatenated display).
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Slc45a2 Mutation:  42 strains or lines available
ES cells used were derived from double heterozygous mice carrying both In(15)21RK and Matp +/uw crossed to 129X1/SvJ males. Genetic background thus includes C57BL/6, DBA/2J, and 129X1/SvJ. The ES cell line used was male.
Original:  J:91142 Chick WS, et al., Modification of an existing chromosomal inversion to engineer a balancer for mouse chromosome 15. Genetics. 2004 Jun;167(2):889-95
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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MGI 6.15
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