Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Mafbtm1Mhs
Name:	MAF bZIP transcription factor B; targeted mutation 1, Michael H Sieweke
MGI ID:	MGI:2677917
Synonyms:	Mafb-, MafBGFP
Gene:	Mafb  Location: Chr2:160205623-160208985 bp, - strand  Genetic Position: Chr2, 80.92 cM
Alliance:	Mafbtm1Mhs page

Germline Transmission:	Earliest citation of germline transmission: J:85746
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Null/knockout, Reporter) Mutation:    Insertion   Mutation details: The endogenous locus was disrupted by the insertion of a cassette containing GFP and neoR. Protein was undetected by Western blot analysis of macrophages obtained from homozygous mutant mice. (J:85746)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	3 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mafb Mutation:	18 strains or lines available

Original:	J:85746 Blanchi B, et al., MafB deficiency causes defective respiratory rhythmogenesis and fatal central apnea at birth. Nat Neurosci. 2003 Oct;6(10):1091-100
All:	7 reference(s)