Summary | Mutation origin | Mutation description | Expression | Phenotypes | Tumor data | Find Mice (IMSR) | References

Symbol:	Pdpk1tm1.2Mlw
Name:	3-phosphoinositide dependent protein kinase 1; targeted mutation 1.2, Margaret A Lawlor
MGI ID:	MGI:2677462
Synonyms:	PDK-
Gene:	Pdpk1  Location: Chr17:24292654-24369898 bp, - strand  Genetic Position: Chr17, 12.23 cM, cytoband A3.3
Alliance:	Pdpk1tm1.2Mlw page

Germline Transmission:	Earliest citation of germline transmission: J:85894
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout) Mutation:    Intragenic deletion   Mutation details: This allele is derived from Pdpk1tm1Mlw by cre mediated excision of the neomycin gene as well as exons 3 and 4. (J:85894)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	3 assay results
In Structures Affected by this Mutation:	14 anatomical structure(s)

List all tumor models in MMHCdb carrying Pdpk1tm1.2Mlw

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pdpk1 Mutation:	138 strains or lines available

Original:	J:85894 Lawlor MA, et al., Essential role of PDK1 in regulating cell size and development in mice. EMBO J. 2002 Jul 15;21(14):3728-38
All:	8 reference(s)