Summary | Mutation origin | Mutation description | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol:	Syn3tm1Pggd
Name:	synapsin III; targeted mutation 1, Paul Greengard
MGI ID:	MGI:2675750
Synonyms:	Syn3tm1Jfe, synapsin III -
Gene:	Syn3  Location: Chr10:85890989-86334760 bp, - strand  Genetic Position: Chr10, 41.95 cM, cytoband C2
Alliance:	Syn3tm1Pggd page

Germline Transmission:	Earliest citation of germline transmission: J:77048
Parent Cell Line:	RW-4 (ES Cell)
Strain of Origin:	129X1/SvJ

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A neomycin selection cassette replaced exon 1. Western blot analysis on brain extracts derived from homozygous mice confirmed that no detectable protein was made from this allele. (J:77048)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Syn3 Mutation:	35 strains or lines available

Original:	J:77048 Feng J, et al., Regulation of neurotransmitter release by synapsin III. J Neurosci. 2002 Jun 1;22(11):4372-80
All:	28 reference(s)