Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol: Rr29Hx Name: regulatory region 29; hemimelic extra toes MGI ID: MGI:1860897 Synonyms: ShhHx Gene: Rr29  Location: unknown  Genetic Position: Chr5, Syntenic Alliance: Rr29Hx page

Skeletal phenotypes of Rr29Hx/Rr29Hx and Rr29Hxl3/Shh+ mice Show the 2 phenotype image(s) involving this allele.

Strain of Origin:

B10.D2-Hc1 H2d H2-T18c/nSnJ

Allele Type:    Spontaneous (Modified regulatory region) Mutation:    Single point mutation   Rr29Hx involves 1 genes/genome features (Lmbr1) View all   Mutation details: This spontaneous mutation is the result of a G-to-A transition in a conserved Shh enhancer element located in intron 5 of the Lmbr1 gene. The mutation is located 145 bp 3' of the Hxl3 mutation. (J:84551, J:87798) Inheritance:    Semidominant

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	22 assay results
In Structures Affected by this Mutation:	9 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Rr29 Mutation:	2 strains or lines available

Original:	J:13476 Dickie MM, Hemimelic extra toes, Hx. Mouse News Lett. 1968;38:24
All:	16 reference(s)