Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Nxnl11Jus13
Name:	nucleoredoxin; lethal, Chr 11, Justice 13
MGI ID:	MGI:2671884
Synonyms:	NxnJ13
Gene:	Nxn  Location: Chr11:76148052-76289967 bp, - strand  Genetic Position: Chr11, 45.92 cM
Alliance:	Nxnl11Jus13 page

Strain of Origin:	C57BL/6J
Project Collection:	Mutagenesis for Dev. Defects

Allele Type:    Chemically induced (ENU) Mutation:    Single point mutation   Mutation details: This phenotypic mutant was identified in an ENU mutagenesis screen at the Baylor College of Medicine. A T-to-A point mutation occurs two base pairs after exon 6, resulting in alteration of a consensus splice donor sequence. RT-PCR and sequencing showed that the mutation results in aberrant splicing of the transcript. A noncomplementation test with a knockout allele confirmed that the mutation in this gene is responsible for the mutant phenotype. (J:161341) Inheritance:    Recessive

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nxn Mutation:	502 strains or lines available

Original:	J:85113 Kile BT, et al., Functional genetic analysis of mouse chromosome 11. Nature. 2003 Sep 4;425(6953):81-6
All:	3 reference(s)