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Lmo2tm2(cre)Thr
Targeted Allele Detail
Summary
Symbol: Lmo2tm2(cre)Thr
Name: LIM domain only 2; targeted mutation 2, Terence H Rabbitts
MGI ID: MGI:2671438
Synonyms: Lmo2-cre
Gene: Lmo2  Location: Chr2:103788340-103812223 bp, + strand  Genetic Position: Chr2, 54.46 cM
Alliance: Lmo2tm2(cre)Thr page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:84518
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutation:    Insertion
 
Lmo2tm2(cre)Thr expression driven by 1 gene
 
Mutation detailsSequence encoding cre recombinase was inserted into the endogenous locus via homologous recombination. (J:84518)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Lmo2 (mouse)
Summary of all recombinase alleles driven by Lmo2.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Lmo2 Mutation:  31 strains or lines available
References
Original:  J:84518 Forster A, et al., Engineering de novo reciprocal chromosomal translocations associated with Mll to replicate primary events of human cancer. Cancer Cell. 2003 May;3(5):449-58
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory