About   Help   FAQ
Cx3cr1tm1Ifc
Targeted Allele Detail
Summary
Symbol: Cx3cr1tm1Ifc
Name: C-X3-C motif chemokine receptor 1; targeted mutation 1, Israel F Charo
MGI ID: MGI:2450885
Synonyms: CX3CR1-
Gene: Cx3cr1  Location: Chr9:119877749-119897362 bp, - strand  Genetic Position: Chr9, 71.37 cM
Alliance: Cx3cr1tm1Ifc page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:82033
Parent Cell Line:  RF8 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe entire coding region of the gene was replaced with a floxed neomycin resistance cassette via homologous recombination. (J:82033)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cx3cr1 Mutation:  45 strains or lines available
References
Original:  J:82033 Haskell CA, et al., Targeted deletion of CX(3)CR1 reveals a role for fractalkine in cardiac allograft rejection. J Clin Invest. 2001 Sep;108(5):679-88
All:  10 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/09/2024
MGI 6.23
The Jackson Laboratory