Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Fgfr1tm1Jpa
Name:	fibroblast growth factor receptor 1; targeted mutation 1, Juha Partanen
MGI ID:	MGI:2448986
Synonyms:	Fgfr1f, Fgfr1flox
Gene:	Fgfr1  Location: Chr8:26008808-26067819 bp, + strand  Genetic Position: Chr8, 14.12 cM
Alliance:	Fgfr1tm1Jpa page

Germline Transmission:	Earliest citation of germline transmission: J:81179
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: Several steps of homologous and cre-mediated recombination left single loxP sites flanking exons 8 through 15. The floxed exons encode the transmembrane domain, juxtamembrane domain, and most of the tyrosine kinase domain. (J:83004)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	117 assay results 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	16 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Fgfr1 Mutation:	221 strains or lines available

Original:	J:81179 Trokovic N, et al., Fgfr1 regulates patterning of the pharyngeal region. Genes Dev. 2003 Jan 1;17(1):141-53
All:	64 reference(s)