Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Pou3f1tm1Rsd
Name:	POU domain, class 3, transcription factor 1; targeted mutation 1, Michael G Rosenfeld
MGI ID:	MGI:1857994
Synonyms:	Oct-6lacZ, Scip-LacZ, Tst-1-, Tst-1/Oct-6/SCIP-, tst-1/scip/oct-6
Gene:	Pou3f1  Location: Chr4:124551439-124554448 bp, + strand  Genetic Position: Chr4, 57.86 cM
Alliance:	Pou3f1tm1Rsd page

Germline Transmission:	Earliest citation of germline transmission: J:34460
Parent Cell Line:	J1 (ES Cell)
Strain of Origin:	129S4/SvJae

Allele Type:    Targeted (Null/knockout, Reporter) Mutations:    Insertion, Intragenic deletion   Mutation details: An in-frame lacZ gene followed by a neomycin resistance cassette replaced sequences encoding the entire amino terminus and POU domain. No protein was detected in sections of cerebral cortex by immunohistochemical analysis. (J:34460)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

4 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pou3f1 Mutation:	14 strains or lines available

Original:	J:34460 Bermingham JR Jr, et al., Tst-1/Oct-6/SCIP regulates a unique step in peripheral myelination and is required for normal respiration. Genes Dev. 1996 Jul 15;10(14):1751-62
All:	7 reference(s)