Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Smad4m2Mag
Name:	SMAD family member 4; mutation 2, Terry Magnuson
MGI ID:	MGI:2447204
Gene:	Smad4  Location: Chr18:73772080-73836851 bp, - strand  Genetic Position: Chr18, 49.51 cM
Alliance:	Smad4m2Mag page

Germline Transmission:	Earliest citation of germline transmission: J:80520
Parent Cell Line:	CT129 (ES Cell)
Strain of Origin:	129S/Sv

Allele Type:    Chemically induced (ENU) (Not Specified) Mutation:    Single point mutation   Mutation details: A transtition mutation (A to G) at nucleotide 858 resulted in a threonine to alanine substitution at residue 180 (T180A). (J:80520)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Smad4 Mutation:	43 strains or lines available

Original:	J:80520 Vivian JL, et al., An allelic series of mutations in Smad2 and Smad4 identified in a genotype-based screen of N-ethyl-N- nitrosourea-mutagenized mouse embryonic stem cells. Proc Natl Acad Sci U S A. 2002 Nov 26;99(24):15542-7
All:	1 reference(s)