Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Cd36tm1Frm
Name:	CD36 molecule; targeted mutation 1, Mason W Freeman
MGI ID:	MGI:2447190
Synonyms:	CD36-
Gene:	Cd36  Location: Chr5:17986688-18093799 bp, - strand  Genetic Position: Chr5, 8.11 cM
Alliance:	Cd36tm1Frm page

Germline Transmission:	Earliest citation of germline transmission: J:80658
Parent Cell Line:	J1 (ES Cell)
Strain of Origin:	129S4/SvJae

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: The gene was disrupted by replacement of exons 3-9 with a neomycin resistance cassette via homologous recombination. Absence of gene expression in homozygous mutant animals was verified by Western blot analysis of several organ samples and primary myeloid cells. (J:80658)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cd36 Mutation:	32 strains or lines available

Original:	J:80658 Moore KJ, et al., A CD36-initiated signaling cascade mediates inflammatory effects of beta-amyloid. J Biol Chem. 2002 Dec 6;277(49):47373-9
All:	31 reference(s)