Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Hprt1tm1(FLT1-lacZ)Aird
Name:	hypoxanthine phosphoribosyltransferase 1; targeted mutation 1, William C Aird
MGI ID:	MGI:2447168
Synonyms:	Flt-1-lacZ-Hprt
Gene:	Hprt1  Location: ChrX:52077014-52110536 bp, + strand  Genetic Position: ChrX, 29.31 cM, cytoband A6
Alliance:	Hprt1tm1(FLT1-lacZ)Aird page

Germline Transmission:	Earliest citation of germline transmission: J:80525
Parent Cell Line:	BK4 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Reporter) Mutation:    Insertion   Mutation details: A construct containing the human FLT1 promoter (-748 to +284) adjoined to lacZ was targeted to the Hprt locus. Expression of lacZ by the FLT1 promoter was confirmed by whole mount staining of mutant embryos and postnatal mice. (J:80525)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hprt1 Mutation:	1273 strains or lines available

Original:	J:80525 Minami T, et al., Differential regulation of the von Willebrand factor and Flt-1 promoters in the endothelium of hypoxanthine phosphoribosyltransferase-targeted mice. Blood. 2002 Dec 1;100(12):4019-25
All:	1 reference(s)