Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Hoxd10tm1Mrc
Name:	homeobox D10; targeted mutation 1, Mario R Capecchi
MGI ID:	MGI:1857962
Synonyms:	Hoxd-10-
Gene:	Hoxd10  Location: Chr2:74522268-74525449 bp, + strand  Genetic Position: Chr2, 44.13 cM
Alliance:	Hoxd10tm1Mrc page

Germline Transmission:	Earliest citation of germline transmission: J:44765
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Null/knockout) Mutation:    Insertion     A neomycin resistance cassette disrupted exon 2 of the gene. (J:44765)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	64 assay results
In Structures Affected by this Mutation:	5 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hoxd10 Mutation:	15 strains or lines available

Original:	J:44765 Carpenter EM, et al., Targeted disruption of Hoxd-10 affects mouse hindlimb development. Development. 1997 Nov;124(22):4505-14
All:	7 reference(s)