Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Stam2tm1Sug
Name:	signal transducing adaptor molecule (SH3 domain and ITAM motif) 2; targeted mutation 1, Kazuo Sugamura
MGI ID:	MGI:2446571
Synonyms:	STAM2-
Gene:	Stam2  Location: Chr2:52582213-52632212 bp, - strand  Genetic Position: Chr2, 30.41 cM
Alliance:	Stam2tm1Sug page

Germline Transmission:	Earliest citation of germline transmission: J:80617
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout) Mutation:    Insertion   Mutation details: The endogenous allele was disrupted using molecular techniques. Normal protein was undetected by Western blot analysis of homozygous mutant thymocyte immunoprecipitates. (J:80617)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Stam2 Mutation:	55 strains or lines available

Original:	J:80617 Yamada M, et al., Signal-Transducing Adaptor Molecules STAM1 and STAM2 Are Required for T-Cell Development and Survival. Mol Cell Biol. 2002 Dec;22(24):8648-58
All:	1 reference(s)