Trps1tm1Shiv
Targeted Allele Detail
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| Symbol: |
Trps1tm1Shiv |
| Name: |
transcriptional repressor GATA binding 1; targeted mutation 1, Ramesh A Shivdasani |
| MGI ID: |
MGI:2446569 |
| Synonyms: |
TRPSdelta neogt |
| Gene: |
Trps1 Location: Chr15:50518148-50753859 bp, - strand Genetic Position: Chr15, 19.18 cM
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| Alliance: |
Trps1tm1Shiv page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:80615
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| Parent Cell Line: |
J1 (ES Cell)
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| Strain of Origin: |
129S4/SvJae
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| Allele Type: |
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Targeted (Null/knockout) |
| Mutations: |
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Insertion, Intragenic deletion
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Mutation details: Exon 4, which encodes the GATA-type zinc finger and 15 additional amino acids, was replaced by a floxed neomycin selection cassette inserted by homologous recombination. Mice carrying this allele were bred with transgenic mice expressing cre recombinase to generate Trps1tm1.1Shiv.
(J:80615)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Trps1 Mutation: |
62 strains or lines available
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| Original: |
J:80615 Malik TH, et al., Deletion of the GATA domain of TRPS1 causes an absence of facial hair and provides new insights into the bone disorder in inherited tricho-rhino-phalangeal syndromes. Mol Cell Biol. 2002 Dec;22(24):8592-600 |
| All: |
2 reference(s) |
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Analysis Tools
