Summary | Mutation origin | Mutation description | Expression | Phenotypes | Tumor data | Find Mice (IMSR) | References

Symbol:	Cdx2tm1Fbe
Name:	caudal type homeobox 2; targeted mutation 1, F Beck
MGI ID:	MGI:1857928
Synonyms:	Cdx2-
Gene:	Cdx2  Location: Chr5:147237710-147244059 bp, - strand  Genetic Position: Chr5, 86.86 cM, cytoband G2-G3
Alliance:	Cdx2tm1Fbe page

Germline Transmission:	Earliest citation of germline transmission: J:38772
Parent Cell Line:	W9.5/W95 (ES Cell)
Strain of Origin:	129S1/Sv-Oca2+ Tyr+ Kitl+

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion     A PGK-neomycin resistance cassette replaced 5.9 kb of the gene. (J:38772)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	107 assay results 2 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	11 anatomical structure(s)

List all tumor models in MMHCdb carrying Cdx2tm1Fbe

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cdx2 Mutation:	22 strains or lines available

Original:	J:38772 Chawengsaksophak K, et al., Homeosis and intestinal tumours in Cdx2 mutant mice. Nature. 1997 Mar 6;386(6620):84-7
All:	30 reference(s)