Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	KitlSl-31R
Name:	kit ligand; steel 31 Oak Ridge
MGI ID:	MGI:2445943
Gene:	Kitl  Location: Chr10:99851492-99936278 bp, + strand  Genetic Position: Chr10, 51.4 cM
Alliance:	KitlSl-31R page

Strain of Origin:

C3H/HeRl

Allele Type:    Chemically induced (ENU) Mutation:    Single point mutation   Mutation details: Nucleotide sequencing of Taq-generated RT-PCR products showed that this allele comprises a C-to-T transition resulting in a proline to leucine substitution at position 23 (48 in pre-protein) (p.P23L, p.P48L). (J:80496) Inheritance:    Semidominant

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Kitl Mutation:	92 strains or lines available

Original:	J:80496 Rajaraman S, et al., An allelic series of mutations in the kit ligand gene of mice. I. Identification of point mutations in seven ethylnitrosourea-induced Kitl(Steel) alleles. Genetics. 2002 Sep;162(1):331-40
All:	3 reference(s)