About   Help   FAQ
Sod1tm1Leb
Targeted Allele Detail
Summary
Symbol: Sod1tm1Leb
Name: superoxide dismutase 1, soluble; targeted mutation 1, Russell M Lebovitz
MGI ID: MGI:1857873
Synonyms: Cu,Zn-SOD-, CuZnSOD-, SOD1-, SOD1m1BCM
Gene: Sod1  Location: Chr16:90017650-90023221 bp, + strand  Genetic Position: Chr16, 51.56 cM, cytoband B5-C3
Alliance: Sod1tm1Leb page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:64299
Parent Cell Line:  AB2.1 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprt1b-m2
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsReplacement of exons 1 and 2 with a PGK-hprt expression cassette. Protein was not detected in brain of homozygous mutant mice. (J:64299)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Disease models
Loading...
Expression
In Structures Affected by this Mutation: 15 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Sod1 Mutation:  37 strains or lines available
References
Original:  J:64299 Matzuk MM, et al., Ovarian function in superoxide dismutase 1 and 2 knockout mice. Endocrinology. 1998 Sep;139(9):4008-11
All:  74 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/19/2024
MGI 6.23
The Jackson Laboratory